Open AccessAn alternative synthesis of clindamycin
Author(s) -
Keith Bowden,
P Graham Stevens
Publication year - 2000
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc0010691b
Subject(s) - chemistry , clindamycin , lincomycin , mathematics , medicinal chemistry , antibiotics , biochemistry
A novel synthesis of clindamycin from lincomycin using N-chlorosuccinimide and triphenylphosphine is reported. This results in high yields and avoids the use of tetrachloromethane employed in the current manufacturing process.This article has been corrected. Link to the correction 10.2298/JSC0012975E