Open AccessLupus anticoagulans in patients with recurrent spontaneous abortion and secondary sterility
Author(s) -
K. Jeremić,
Milica Ilić,
M Gojnić,
S Petković,
Aleksandar Ljubić,
L Nikolić,
Sasa Maslac
Publication year - 2005
Publication title -
jugoslovenska medicinska biohemija
Language(s) - English
Resource type - Journals
eISSN - 1452-8193
pISSN - 0354-3447
DOI - 10.2298/jmh0501051j
Subject(s) - medicine , abortion , lupus anticoagulant , systemic lupus erythematosus , sterility , antibody , live birth , anticardiolipin antibodies , systemic lupus , antiphospholipid syndrome , immunology , obstetrics , gynecology , pregnancy , disease , genetics , biology
Antiphospholipid antibodies (lupus anticoagulans and anticardiolipine antibodies) are frequent cause of recurrent spontaneous abortion in patients with secondary sterility. Our aim was to evaluate the frequency of lupus anticoagulans antibodies in patients with recurrent abortions and to analyze their coagulation status relative to health (control) patients. We got the statistical significances (p < 0.05) in number of lupus anticoagulans positive women between the groups. Activated partial tromboplastin time and protrombin time are statistical significant (p < 0.05) higher in analyzed patients with recurrent abortion, which is in agreement of existing lupus anticoagulans activity. Detecting by the time, antiphospholipid antibodies and giving the anticoagulant therapy to the patients, the risk for abortion will be decreased.