Open AccessDevelopment of a closed-loop neural prosthesis for vestibular disorders
Author(s) -
Giovanna J. Di,
Wangsong Gong,
Csilla Haburcakova,
V. Kögler,
J. Carpaneto,
V. Genovese,
Daniel M. Merfeld,
Andreas Demosthenous,
Jean-Philippe Guyot,
K. Hoffmann,
Alain Berthoz,
Manfred Morari,
Silvestro Micera
Publication year - 2010
Publication title -
journal of automatic control
Language(s) - English
Resource type - Journals
eISSN - 2406-0984
pISSN - 1450-9903
DOI - 10.2298/jac1001027d
Subject(s) - neural prosthesis , vestibular system , computer science , vestibular disorders , physical medicine and rehabilitation , neuroscience , audiology , medicine , psychology
Vestibular disorders can cause severe problems including spatial disorientation, imbalance, nausea, visual blurring, and even cognitive deficits. The CLONS project is developing a closed-loop, sensory neural prosthesis to alleviate these symptoms [1]. In this article, we outline the different components necessary to develop this prosthetic. A short version of this work was presented in the NEUREL 2010 [1]. Conceptually, the prosthesis restores vestibular information based on inertial sensors rigidly affixed to the user. These sensors provide information about rotational velocity of the head; the prosthetic then transfers the information to the vestibular nerve via electrical stimulation. Here we present a project overview, development details, and summarize our progress in animal models and selected human volunteers