Open AccessThe application of HP-GFC chromatographic method for the analysis of oligosaccharides in bioactive complexes
Author(s) -
Ivan Savić,
Goran Nikolić,
Ivana Savić,
Milorad D. Cakić
Publication year - 2009
Publication title -
hemijska industrija
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.147
H-Index - 19
eISSN - 2217-7426
pISSN - 0367-598X
DOI - 10.2298/hemind0905415s
Subject(s) - metal , oligosaccharide , metal ions in aqueous solution , pullulan , chemistry , degree of polymerization , polymerization , ligand (biochemistry) , dextran , polymer chemistry , organic chemistry , polymer , polysaccharide , biochemistry , receptor
The aim of this work was to optimize a GFC method for the analysis of bioactive metal (Cu, Co and Fe) complexes with olygosaccharides (dextran and pullulan). Bioactive metal complexes with olygosaccharides were synthesized by original procedure. GFC was used to study the molecular weight distribution, polymerization degree of oligosaccharides and bioactive metal complexes. The metal bounding in complexes depends on the ligand polymerization degree and the presence of OH groups in coordinative sphere of the central metal ion. The interaction between oligosaccharide and metal ions are very important in veterinary medicine, agriculture, pharmacy and medicine