Open AccessSimultaneous ultrafiltration and diafiltration
Author(s) -
Zoltan Z. Zavargo,
N Miodrag Tekic,
Slavko Djuric,
M Darko Krstic
Publication year - 2002
Publication title -
hemijska industrija
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.147
H-Index - 19
eISSN - 2217-7426
pISSN - 0367-598X
DOI - 10.2298/hemind0205204z
Subject(s) - diafiltration , ultrafiltration (renal) , dilution , permeation , chemistry , volume (thermodynamics) , chromatography , constant (computer programming) , membrane , thermodynamics , computer science , microfiltration , biochemistry , physics , programming language
A model with simultaneous ultrafiltration and diafiltration, which includes the rejection coefficients, is presented in this study. Adding a diafiltration solution at a constant, lower rate than the filtrate rate results in a constant decrease of the solution volume in the tank. This enables the simultaneous attainment of the desired macrosolute concentration and microsulute dilution. The proposed model, based on incomplete macrosolute rejection and incomplete mi-crosolute permeation through a membrane, as well as constant permeate flux, is compared to the classical constant volume, diafiltration process. The obtained results show that less diafiltration volume is necessary with this process. Simultaneously, the duration of the process, for higher purification requirements, is shorter in this case