Open AccessSynthesis, X-ray and antimicrobial activity of isatin-3-phenylhydrazone
Author(s) -
Sandra S. Konstantinović,
Á. Kapor,
Blaga Radovanović,
Andréa Deák
Publication year - 2008
Publication title -
chemical industry and chemical engineering quarterly
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.189
H-Index - 26
eISSN - 2217-7434
pISSN - 1451-9372
DOI - 10.2298/ciceq0801027k
Subject(s) - isatin , proteus vulgaris , candida albicans , antimicrobial , chemistry , staphylococcus aureus , fourier transform infrared spectroscopy , escherichia coli , nuclear chemistry , pseudomonas aeruginosa , microbiology and biotechnology , organic chemistry , bacteria , biology , biochemistry , genetics , physics , quantum mechanics , gene
Isatin-3-phenylhydrazone was synthesized and X-ray crystal structure of this compound has been solved. Its structure was also established using FTIR, UV/Vis and H-NMR spectroscopic method. The compound was tested for antimicrobial activity against Staphylococcus aureus, Bacillus subtilus, Enterococcus D, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Candida albicans. Stability of isatin-3-phenylhydrazone toward UV-A irradiation has been studied in this work. Isatin derivative undergoes bleaching following first-order kinetics.