Synthesis, X-ray and antimicrobial activity of isatin-3-phenylhydrazone | Zendy

Sandra Konstantinović | Zendy; Á. Kapor | Zendy; Blaga Radovanović | Zendy; Andrea Deák | Zendy

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Synthesis, X-ray and antimicrobial activity of isatin-3-phenylhydrazone

Author(s) -

Sandra Konstantinović,

Á. Kapor,

Blaga Radovanović,

Andrea Deák

Publication year - 2008

Publication title -

chemical industry and chemical engineering quarterly

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.189

H-Index - 26

eISSN - 2217-7434

pISSN - 1451-9372

DOI - 10.2298/ciceq0801027k

Subject(s) - isatin , proteus vulgaris , candida albicans , antimicrobial , chemistry , staphylococcus aureus , fourier transform infrared spectroscopy , escherichia coli , nuclear chemistry , pseudomonas aeruginosa , microbiology and biotechnology , organic chemistry , bacteria , biology , biochemistry , genetics , physics , quantum mechanics , gene

Isatin-3-phenylhydrazone was synthesized and X-ray crystal structure of this compound has been solved. Its structure was also established using FTIR, UV/Vis and H-NMR spectroscopic method. The compound was tested for antimicrobial activity against Staphylococcus aureus, Bacillus subtilus, Enterococcus D, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Candida albicans. Stability of isatin-3-phenylhydrazone toward UV-A irradiation has been studied in this work. Isatin derivative undergoes bleaching following first-order kinetics.

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