Open AccessLung protective mechanical ventilation and rescue therapy for severe hypoxemia
Author(s) -
Z Terziski,
Vanja Misic,
Marija Milenković,
Vesna Bumbaširević,
B Jovanović,
Irena Jozić
Publication year - 2016
Publication title -
acta chirurgica iugoslavica
Language(s) - English
Resource type - Journals
eISSN - 2406-0887
pISSN - 0354-950X
DOI - 10.2298/aci1602053t
Subject(s) - medicine , hypoxemia , ards , lung , mechanical ventilation , refractory (planetary science) , rescue therapy , anesthesia , oxygenation , ventilation (architecture) , pulmonary edema , acute respiratory distress , diffuse alveolar damage , intensive care medicine , cardiology , mechanical engineering , physics , astrobiology , engineering
Acute respiratory distress syndrome (ARDS) is a clinical syndrome of non-cardiogenic pulmonary oedema associated with bilateral pulmonary infiltrates, stiff lungs and refractory hypoxemia. Despite our improved understanding of lung injury, advancements in application of lung protective ventilation to prevent ventilatory induced lung injury (VILI), lung injury persist or progresses in some patients, leading to refractory hypoxemia. We review several ?rescue? strategies for severe hypoxemia, including lung recruitment maneuver, prone positioning, inhaled vazodilatators, and extracorporal membrane oxygenation.