Case of leptosuccin induced malignant hyperthermia in a patient with GIST of the rectum

Malignant hyperthermia (MH) is a form of myopathy that is usually triggered by volatile anaesthetics such as halothane, sevoflurane and des flurane and depolarising muscle relaxants such as succinylcholine. Pathologic response in MH inc1ude increase in oxygen consumption, increase in endtidal C02, tachycardia, hyperthermia, hyperkalemia and muscle rigidity. Immediate recognition and treatment are crucial to avoid lethal outcome. Molecular genetic studies have confirmed that ryanodine muscle receptors are responsible for MH. We present a case of leptosuccin induced MH with masseter muscle rigidity, mild pC02 increase (6.3 kPa), elevated body temperature measured with esophageal temperature probe (39.5°C) tachycardia (115 beats/min) and respiratory and metabolic acidosis (pH was 7,23) in a patient who underwent low anterior resection of the rectum for gast rointestinal stromal tumor (GIST) of the rectum