Open AccessComparasion of granisetron and metoclopramide for prevention of nausea and vomiting following total cystectomy and ileal conduit
Author(s) -
Nebojša Ladjević,
Likic I. Ladjevic,
B. Krivic,
J. Filimonovic,
M. Acimovic,
Danijela Dragičević,
Rajka Argirović
Publication year - 2007
Publication title -
acta chirurgica iugoslavica
Language(s) - English
Resource type - Journals
eISSN - 2406-0887
pISSN - 0354-950X
DOI - 10.2298/aci0702019l
Subject(s) - granisetron , medicine , metoclopramide , vomiting , nausea , cystectomy , anesthesia , electrical conduit , antiemetic , bladder cancer , cancer , mechanical engineering , engineering
The objective of this study was to examine the use of granisetron in actual clinical practice and to compare effect of dose of 1 mg granisetron after total cystectomy plus ileal conduit with group of patients which received metoclopramide. Granisetron established total contol of PONV in 93,33% patients. Granisetron is 40% more effective in PONV control than metoclopramide. Only minimal nausea epizodes were observed in early postoperative period in patients who had received low dose of granisetron (1 mg i.v.).