Open Access111 in labeled antibodies in the detection of colorectal carcinoma
Author(s) -
M Vera Artiko,
Vladimir Obradović,
Mladen Davidović,
Nataša Petrović,
Nataša Petrović,
V Zoran Krivokapic,
Dragutin Kecmanović,
G Adanja,
D. Sobić,
Sladjana Pavlović,
R Rebić
Publication year - 2003
Publication title -
acta chirurgica iugoslavica
Language(s) - English
Resource type - Journals
eISSN - 2406-0887
pISSN - 0354-950X
DOI - 10.2298/aci0304043a
Subject(s) - immunoscintigraphy , medicine , radiology , colorectal cancer , antibody , carcinoma , oncology , pathology , monoclonal antibody , cancer , immunology , radioimmunotherapy
The aim of the study is detection of the recurrences and metastases of colorectal carcinomas using (111)In labelled antibodies B72.3 in 14 patients. With tomography, we can access better distinction of tumour in comparison to other structures and estimation of its size. Other imaging methods (CT, US) have advantage in detection of liver metastases, while immunoscintigraphy is more specific for the assessment of malignant abdominal tumours and extrahepatic metastases. The first results point out that Oncoscint CR-103 can be useful in diagnosis of recurrences and metastases of colorectal carcinoma, viability assessment after radiotherapy and in the choice of the adequate surgical treatment in dependence of the spread of the disease.