Open AccessThe influence of vitamin E supplementation on the oxidative status of rat liver
Author(s) -
Siniša Đurašević,
Jelena Djordjević,
Nebojša Jasnić,
Iva Lakić,
Predrag Vujović,
Gordana Cvijić
Publication year - 2010
Publication title -
archives of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 25
eISSN - 1821-4339
pISSN - 0354-4664
DOI - 10.2298/abs1003677d
Subject(s) - catalase , lipid peroxidation , vitamin e , antioxidant , oxidative phosphorylation , chemistry , hydrogen peroxide , vitamin , medicine , endocrinology , liver metabolism , vitamin c , liver tissue , oxidative damage , biochemistry , biology
We tested to see if the additional intake of vitamin E in the form of α-tocopheryl-succinate would improve liver antioxidative protection. Thus, we studied the tissue oxidative status in rats supplemented by two doses of the antioxidant over a four week period of time. Our results confirmed that the additional intake of vitamin E decreased the liver lipid peroxidation level and SOD activity level and preserved its vitamin C content. However, the hydrogen peroxide content and catalase activity remained unchanged, probably due to the mechanism of vitamin E liver metabolism.