Open AccessLimbic autoimmune encephalitis with antibodies to glutamate decarboxylase (GAD)
Author(s) -
Л. У. Улуханова,
М. М. Яралиев,
С. М. Аттаева
Publication year - 2020
Publication title -
detskie infekcii
Language(s) - English
Resource type - Journals
eISSN - 2618-8139
pISSN - 2072-8107
DOI - 10.22627/2072-8107-2020-19-2-67-71
Subject(s) - glutamate decarboxylase , limbic encephalitis , autoimmune encephalitis , antibody , glutamate receptor , immunology , stiff person syndrome , encephalitis , medicine , disease , autoantibody , neuroscience , biology , pathology , enzyme , receptor , virus , biochemistry
Limbic encephalitis (LE) is a rare neurological syndrome, in most cases has a paraneoplastic nature, but recently there has been a large number of observations of idiopathic autoimmune LE associated with antibodies to neuronal membrane proteins. A clinical case of a disease in a 13-year-old patient with the detection of antibodies to glutamate decarboxylase (GAD) is described. The debut of the disease is marked by a decrease in memory for current events after the first convulsive attack during 2 months.