Open AccessKlebsiella pneumoniae cryptogenic liver abscess and endophthalmitis – a case report and review of literature
Author(s) -
Mihai Grecescu,
Monica Grecescu,
Andreea Smarandache,
C Brănescu,
Anca Anghelache,
Anca Silvia Dumitriu,
Stana Păunică,
Andreea Costea
Publication year - 2021
Publication title -
journal of mind and medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2601-4920
pISSN - 2392-7674
DOI - 10.22543/7674.82.p330335
Subject(s) - medicine , evisceration (ophthalmology) , klebsiella pneumoniae , endophthalmitis , liver abscess , abscess , cefuroxime , cellulitis , surgery , orbital cellulitis , septic shock , meropenem , antibiotics , sepsis , pathology , antibiotic resistance , biochemistry , chemistry , alternative medicine , escherichia coli , biology , microbiology and biotechnology , gene
Klebsiella pneumoniae has emerged as the predominant pathogenic agent of liver abscess in Asia, and the incidence is increasing worldwide. Hypervirulent strains are associated with septic metastatic dissemination in the eyes, lungs, and central nervous system, causing severe morbidity. We present the case of a 54year old man, with no previous comorbidities, admitted in emergency for the blind red painful eye. Further investigation documented septic endophthalmitis with transscleral extension and orbital cellulitis. Thoraco-abdominal computed tomography evidenced a hepatic abscess as the locus of the primary infection. Intravenous antibiotherapy with cefuroxime, followed by meropenem and vancomycin were efficient for managing the hepatic abscess. However, as the eyeball was perforated at the admission, evisceration was performed. The vitreous sample revealed Klebsiella pneumoniae, with a positive string test as the etiologic agent. The diagnostic and therapeutic management required a permanent collaboration between an ophthalmologist, infectious diseases specialist, surgeon, and radiologist.