Open AccessBiochemical and echocardiographic markers for the early detection of car detection of cardiotoxicity under monoclonal antibodies ther xicity under monoclonal antibodies therapy
Author(s) -
Ionela-Emilia Popovici,
Angela Cozma,
Olga Hilda Orăşan,
George Ciulei,
Ana Maria Poenar,
Cristina Buchman,
Simina Ţărmure,
Sorina Secara,
Adela Sitar-Tăut,
Teodora Alexescu,
Andrada Lazar,
Vasile Negrean,
Lucia Maria Procopciuc
Publication year - 2021
Publication title -
journal of mind and medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2601-4920
pISSN - 2392-7674
DOI - 10.22543/7674.81.p3443
Subject(s) - medicine , cardiotoxicity , monoclonal antibody , cancer therapy , adverse effect , antibody therapy , cancer , oncology , trastuzumab , intensive care medicine , antibody , immunology , chemotherapy , breast cancer
The progress made over the past years in the field of cancer therapy has led to a significant decrease in cancer mortality, but these therapies have many adverse effects, cardiovascular effects being among the most frequent ones. For increasing lifelong expectancy of surviving cancer patients, cardiac monitoring represents an important task. Current studies and practice recommend echocardiography using strain analysis for monitoring the cardio toxic effects of cancer therapy. The potential of combining imaging techniques with biomarkers for the early detection and diagnosis seems a promising path for future research.