Open AccessPost mortem changes: challenges in drug analysis in the diagnosis of deaths from intoxication
Author(s) -
Marina Camargo Galera,
Luciana Grazziotin RossatoGrando
Publication year - 2021
Publication title -
drug analytical research
Language(s) - English
Resource type - Journals
ISSN - 2527-2616
DOI - 10.22456/2527-2616.111711
Subject(s) - forensic toxicology , forensic science , sampling error , medicine , redistribution (election) , peripheral blood , sampling (signal processing) , pathology , computer science , chemistry , statistics , chromatography , mathematics , observational error , filter (signal processing) , politics , political science , veterinary medicine , law , computer vision
In forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences in these analyses. This study aimed to perform a bibliographic review through Pubmed database within a 10-year period of time, using the keywords: forensic analysis AND redistribution. We observed that for quantitative analyses the preferred matrix is blood from peripheral vessels, and when it is not available, vitreous humor is a great specimen for choice.