Open AccessMethodologies for preliminary assessment of the biocompatibility of endodontic materials: a review.
Author(s) -
Roberta Kochenborger Scarparo,
Elaine Freitas Fachin,
Fabiana Soares Grecca
Publication year - 2009
Publication title -
revista da faculdade de odontologia de porto alegre
Language(s) - English
Resource type - Journals
eISSN - 2177-0018
pISSN - 0566-1854
DOI - 10.22456/2177-0018.11943
Subject(s) - biocompatibility , compatibility (geochemistry) , computer science , biochemical engineering , dentistry , biomedical engineering , materials science , engineering , medicine , composite material , metallurgy
This literature review discusses the objectives, importance and limitations of the experimental models and evaluation criteria used in preliminary studies of the biological compatibility of endodontic materials. It was ascertained that this is an important stage in determining the biocompatibility of materials and one which, within certain limits, allows the reaction of tissues directly involved in endodontic treatment to be predicted. However, the methodology used by these studies has not been standardized. The type of tissues investigated, the experimental periods observed and the methods used to analyze inflammatory response are considered fundamental requirements for designing experiments and understanding their results.