Open AccessA MIXED INFECTION OF INTESTINAL MICROSPORIDIOSIS AND SALMONELLOSIS IN A 2-YEAR-OLD BOY WITH INHERITED IMMUNODEFICIENCY SYNDROME
Author(s) -
Azlin Muhammad,
Mekadina Bernadus,
Rozliana Hanim Mat Hasan,
Wathiqah Wahid
Publication year - 2021
Publication title -
journal of health and translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 7
eISSN - 2289-392X
pISSN - 1823-7339
DOI - 10.22452/jummec.vol24no2.5
Subject(s) - microsporidiosis , enterocytozoon bieneusi , microsporidia , diarrhea , albendazole , immunodeficiency , immunology , medicine , virology , biology , immune system , microbiology and biotechnology , surgery , spore
Gastrointestinal microsporidiosis is a major cause of chronic diarrhea in people with acquired immune deficienc syndrome. However, it can also affect individuals with inherited or congenital immunodeficiency. We reported a case of intestinal microsporidiosis and salmonellosis in a young boy with Hyper IgM syndrome. He presented with severe diarrhea and fever for 5 days. Stool examination showed heavy infection of Microsporidia spp. PCR confirmed the species as Enterocytozoon bieneusi. He was treated with albendazole for 25 days which abated the symptoms. To our knowledge, this is the first reported case of intestinal microsporidiosis in inherited immunodeficiency, X-linked Hyper IgM (XHIGM).