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Pengembangan Sediaan Krim Pencerah Kulit dari Kombinasi Ekstrak Rimpang Temulawak (Curcuma Xanthorrhiza Roxb) dan Ekstrak Biji Kacang Kedelai (Gl ycine Max (L.) Merill)
Author(s) -
Leni Nurlina Yanti,
Anny Victor Purba,
Ratna Djamil
Publication year - 2019
Publication title -
bulletin penelitian kesehatan/buletin penelitian kesehatan
Language(s) - English
Resource type - Journals
eISSN - 2338-3453
pISSN - 0125-9695
DOI - 10.22435/bpk.v47i1.1385
Subject(s) - curcuma , traditional medicine , rhizome , horticulture , chemistry , biology , medicine
Javanese turmeric (Curcuma xanthorrhiza) and soybean (Glycine max L. Merill) are natural ingredientsthat can be used to treat face skin. The aim of this study was to formulate extracts of Javanese turmeric andsoybean in the form of skin lightening cream preparations.. In this experiment, four cream formulationswere made containing a combination of javanese tumeric extract with concentrations of 1%, 3%, 5% and10% and soybean extract with concentrations of 5% and 15%. Accelerated cream formulations stabilitytest for 1 month was tested by observing the results of its storage at low temperatures, room temperatureand high temperature which included organoleptic observation, pH and homogeneity where each formulashowed physical stability for 4 weeks, pH average 4.5-5.0, and no change in cream color. The irritationtest was tested by using the acute dermal irritation method using rabbits and was declared safe and notirritating. The effectiveness test was measured by applying a combination cream to the respondents andmeasuring the brightness of the skin using a Dermalab examination measured after using the cream.The combination cream with a variation of 10% javanese tumeric concentration and 15% soybeanconcentration was the highest L* score in lightening the skin. Key words: Curcuma rhizome extract; soybean seed extract; cream;skin lingkening        

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