Open AccessDiarrhoea in Patients with COVID-19
Author(s) -
А. А. Шептулин
Publication year - 2020
Publication title -
rossijskij žurnal gastroènterologii, gepatologii, koloproktologii
Language(s) - English
Resource type - Journals
eISSN - 2658-6673
pISSN - 1382-4376
DOI - 10.22416/1382-4376-2020-30-6-51-56
Subject(s) - diarrhea , covid-19 , incidence (geometry) , epidemiology , medicine , coronavirus , intensive care medicine , immunology , virology , physics , disease , outbreak , infectious disease (medical specialty) , optics
Aim . Revision of possible causes of diarrhoea in patients with the COVID-19 infection. Key points . Apart from respiratory symptoms, patients with the COVID-19 infection may also express gastrointestinal complaints, more frequently of diarrhoea (2–40% incidence rate). The causes of diarrhoea may relate to the virus direct interaction with the angiotensin-converting enzyme 2 (ACE2) receptors in mucosa, its impact on the intestinal microbiota and therapeutic side eects. The possible occurrence of diarrhoea as a leading clinical manifestation of the coronavirus infection hampers its timely diagnosis. Published evidence on the impact of diarrhoea on the course of COVID-19 is contradictory. Conclusion . Epidemiological and clinical aspects of this problem require further research.