Open AccessDEFENSINS-a AT AN EARLY AGE IN RATS WITH ACUTE SOMATIC PAIN
Author(s) -
И. М. Быков,
И. М. Быков,
В. В. Алексеев,
В. В. Алексеев
Publication year - 2019
Publication title -
vestnik rossijskogo universiteta družby narodov. seriâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2313-0261
pISSN - 2313-0245
DOI - 10.22363/2313-0245-2019-23-1-19-24
Subject(s) - medicine , somatic cell , peripheral blood , physiology , anesthesia , biology , biochemistry , gene
This article presents the results of studies on the reaction of α-defensins to acute somatic pain in newborn rats and in the early puberty period. Studies were carried out on white mongrel rats for three hours after pain exposure. The level of α-defensins was determined by enzyme immunoassay. During the experiments, a short-term increase in the level of α-defensins in newborns and rats in the early puberty period was revealed. At the same time, in animals of one month of age a two-phase, labile reaction of an increase in the level of α-defensins in peripheral blood occurs.