Open AccessFactors of nonspecific resistance in residents of the Murmansk region and the republic of Karelia
Author(s) -
В. И. Демидов,
А. А. Троценко,
Ю. Н. Закревский,
Л. В. Милякова
Publication year - 2021
Publication title -
morskaâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2587-7828
pISSN - 2413-5747
DOI - 10.22328/2413-5747-2020-6-4-29-37
Subject(s) - glycogen , resistance (ecology) , immunity , peripheral blood , physiology , biology , immunology , immune system , endocrinology , ecology
The aim of the research was to study the factors of nonspecic resistance in residents of the Murmansk region and the Republic of Karelia and the possible inuence of various natural and industrial environmental factors on them. Materials and methods : the indicators of cellular and humoral immunity were studied, evaluated in 2224 people living in the Murmansk region (n=1118) and in the Republic of Karelia (n=1106), for the period from 2001 to 2018. The methods used to study were buccal tests, bactericidal activity of the skin, cytochemical studies (glycogen, alkaline phosphatase) of peripheral blood and differential analysis of erythrocytes. According to the data obtained, the indices of nonspecic resistance in residents of the Murmansk region are on average within the normal range, in contrast to those in the Republic of Karelia. Results : the studies carried out revealed that human blood indices are interrelated with the indices of his nonspecic immunity when adapting to unfavorable environmental conditions in industrial cities. The following blood parameters of the inhabitants of the studied areas reacted to regional natural and industrial factors: glycogen in lymphocytes and neutrophils, basophils, monocytes, leukocytes, segmented neutrophils. Complex methods for studying the nonspecic resistance of the organism can be recommended as an express diagnosis of the inuence of environmental factors on the state of the human body as a whole.