Open AccessMODERN METHODS OF DIAGNOSTIC IMAGING OF GLIOMAS
Author(s) -
Н. А. Костеников,
A. V. Pozdnyakov,
V. F. Dubrovskaya,
O. Yu. Mirolyubova,
Yu. R. Ilyushchenko,
A. A. Stanzhevsky
Publication year - 2019
Publication title -
lučevaâ diagnostika i terapiâ
Language(s) - English
Resource type - Journals
eISSN - 2079-5351
pISSN - 2079-5343
DOI - 10.22328/2079-5343-2019-10-2-15-23
Subject(s) - positron emission tomography , magnetic resonance imaging , medicine , multislice , radiology , single photon emission computed tomography , nuclear medicine , preclinical imaging , tomography , in vivo , biology , microbiology and biotechnology
The review presents an analysis of the literature on the diagnosis of gliomas and the study of their structural and biological features based on implementation of new techniques in clinical practice of diagnostic imaging. These techniques include perfusion technologies for multislice spiral computed tomography (MSCT), magnetic resonance imaging (MRI), functional MRI, proton magnetic resonance spectroscopy (MRS), single photon emission computed tomography (SPECT), and positron emission tomography (PET) with various radiopharmaceuticals (RPHs), first and foremost, labeled amino acids, such as 11 C-L-methionine and 18 F-Fluoroethyltyrosine. There is presented that with the application of these two methods (MRI and PET), the most important biochemical processes underlying oncogenesis of malignant tumors might be studied by non-invasive way. The obtained data can be crucial for an early detection of tumor lesions, staging the pathological process, rationale for therapeutic tactics, personalization of treatment, evaluation of the efficiency of therapy at early stages and prognosis of the disease result.