PERFUSION COMPUTER TOMOGRAPHY OF THE PANCREAS. RESEARCH TECHNIQUE. PERFUSION INDICATORS IN THE NORMAL

Purpose of the study: optimization of the technique and study of the possibilities of perfusion computed tomography (PCT) in assessing the functional state of the pancreatic parenchyma in normal conditions. Materials and methods. PCT was performed in 30 patients with a lack of history and clinical and laboratory data indicating the presence of pancreatic disease, which were examined for other pathological conditions. Using the standard protocol and the deconvolution method, a quantitative assessment of the average perfusion indices in the head, body and tail of the pancreas was performed, and a qualitative analysis of the state of its parenchyma on color parametric maps. Results. The pancreas is an organ with high blood flow rates (BF 136±6,74 ml/100 g/min), blood volume (BF 16,6±0,67 ml/100 g/min), characterized by bright red staining on the corresponding parametric maps. The pancreas is characterized by average values of the average transit time of the contrast agent (MTT 10,25±0,47 s) and the time to maximum tissue density (TTP 17,3±0,6 s), green parenchyma staining on the corresponding parametric maps, low permeability of the capillary walls (PS 3,5±0,72 ml/100 g/min) and blue staining on the permeability map. No statistically significant difference in the average values of perfusion indices in the head, body and tail of the pancreas and the dependence of perfusion parameters on the age of the patients was revealed. Conclusion PCT is an informative method of quantitative and qualitative assessment of the functional state of the pancreatic parenchyma.