Open AccessTHE TECHNIQUE OF MAGNETIC RESONANCE IMAGING WITH DYNAMIC CONTRAST ENHANCEMENT WITH FOCAL BENIGN LUNG FORMATION
Author(s) -
Peter M. Kotlyarov,
I. D. Lagcueva,
Н. И. Сергеев,
E. V. Egorova,
Natalya Chernichenko,
V. А. Solodkiy
Publication year - 2018
Publication title -
lučevaâ diagnostika i terapiâ
Language(s) - English
Resource type - Journals
eISSN - 2079-5351
pISSN - 2079-5343
DOI - 10.22328/2079-5343-2018-9-3-69-74
Subject(s) - magnetic resonance imaging , contrast (vision) , aorta , intensity (physics) , lung , dynamic contrast , nuclear medicine , nuclear magnetic resonance , region of interest , medicine , radiology , physics , optics
MRT with dynamic contrast enhancement has not found wide application in lung pathology, there are no clear recommendations for its implementation, no criteria for the goodness of the changes have been developed. The aim: of the study was to clarify the procedure for analyzing the data of DKU-MRI, the search for predictors of the quality of focal changes in the lungs. DKE-MRT performed 28 patients with verified benign changes in the lungs at a magnetic resonance tomograph of 1,5 T. As the analysis shows, the use of relative rather than absolute values with the calculation of the contrast index (CI), reflecting the degree of accumulation of a paramagnetic substance in the object of investigation relative to the main anatomical landmark-aorta, is a reliable sign of angiogenesis. In this case, it is necessary to focus on the zones of maximum intensity of the MR signal of the structure under study, the value of ROI can vary considerably. The CI in the hamartomas was 0,23–0,35. In the scar tissue, the CI values did not practically change throughout the study, being 0,21–0,25 relative to the peak density in the aorta. CI soft tissues and benign focal lesions of the lungs, the form of the curve of the paramagnetic circulation was comparable, being 0,25–0,3 relative to the peak density to the aorta. When analyzing the DKE-MRT curves, the concentration/time should be oriented to the zones of maximum intensity of the MR signal from vascular structures, focal lesions of the lungs, soft tissues of the back, while the ROI area is of no fundamental importance. As a criterion of good-quality focal formation of the lung should be guided by CI in soft tissues.