Open AccessAUTOCHTHONOUS CASE OF CUTANEOUS LEISHMANIASIS IN HIV INFECTED PATIENT
Author(s) -
L. Ermakova,
N. Golovchenko,
С. А. Нагорный,
Н. Ю. Пшеничная,
Л. А. Аванесова,
А. С. Журавлев
Publication year - 2019
Publication title -
vič-infekciâ i immunosupressii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 4
eISSN - 2078-1792
pISSN - 2077-9828
DOI - 10.22328/2077-9828-2019-11-1-75-80
Subject(s) - medicine , leishmaniasis , human immunodeficiency virus (hiv) , nostril , visceral leishmaniasis , leishmania , viral load , antiretroviral treatment , cutaneous leishmaniasis , dermatology , surgery , immunology , antiretroviral therapy , nose , parasite hosting , world wide web , computer science
Single cases of autochthonous visceral leishmaniasis are registered in the Crimea and Dagestan. The article presents the first case of autochthonous cutaneous leishmaniasis in an HIV infected resident of the Republic of Dagestan, where this disease had not previously been registered. The diagnosis was made on the basis of a parasitological study of material taken from an ulcer on the border between the upper lip and the right nostril. Examination of the patient revealed a high burden of HIV (4 473 014 copies/ml) and a low level of CD4+ (76×10 6 /l; 9%), which indicated an advanced stage of HIV infection. The patient underwent antiretroviral therapy (treatment with amphotericin B), against which a good result was obtained. A decrease in viral load and an increase in the content of CD4 lymphocytes in the blood were noted. A scar has formed on the site of a leishmaniasis ulcer.