Open AccessComparison of the effect of dexmedmotidine and ketamine on controlling pain after cesarean section via intra-peritoneal method
Author(s) -
Alireza Kamali,
Maryam Maktabi,
Zoha Khademi,
Taha Fereidooni
Publication year - 2019
Publication title -
journal of contemporary medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2415-1629
pISSN - 2413-0516
DOI - 10.22317/jcms.v5i4.598
Subject(s) - ketamine , medicine , anesthesia , visual analogue scale , saline , opioid , postoperative pain , pain score , surgery , receptor
Objectives: The present study aimed to compare the effect of dexmedmotidine and ketamine on controlling pain after cesarean section via intra-peritoneal method.
Methods: In this clinical and double-blind clinical trial, patients were randomly divided into two groups (dexmedmotidine and ketamine). In the first group, 5 mg / kg ketamine and 1 mg / kg dexmedetomidine were injected in 100 mg normal saline. Pain score was measured on the basis of the visual analog pain scale during the recovery at 4, 6 and 12 hours after the surgery. The data were then analyzed by SPSS (version 20).
Results: 70 patients participated in the study. The results showed that the mean pain scores were the same in different postoperative hours in patients (P≥0.05). The mean opioid use in the ketamine group was lower than inter-peritoneal dexmedmotidine (P = 0.03). Moreover, the mean postoperative analgesia in the ketamine group was higher than inter-peritoneal dexmedmotidine (P = 0.04).
Conclusion: According to the results, the mean opioid consumed in the ketamine group was less than inter-peritoneal dexmedmotidine. Additionally, the mean postoperative analgesia in the ketamine group was higher than that of inter-peritoneal dimethomidine. Therefore, it can be concluded that ketamine has a better effect on reducing pain after cesarean section.