Open AccessReversible Cerebral vasoconstriction syndrome associated with the use of sibutramine
Author(s) -
Joseph Franklin Chenisz da Silva,
Caio César Demore,
Felipe Ibiapina dos Reis,
Gabriel Abrahão Stoliar,
Matheus Kahakura Franco Pedro,
André Giacomelli Leal
Publication year - 2021
Publication title -
jornal brasileiro de neurocirurgia
Language(s) - English
Resource type - Journals
eISSN - 2446-6786
pISSN - 0103-5118
DOI - 10.22290/jbnc.v32i2.1955
Subject(s) - reversible cerebral vasoconstriction syndrome , vasoconstriction , medicine , headaches , anesthesia , stroke (engine) , cardiology , surgery , mechanical engineering , engineering
The reversible cerebral vasoconstriction syndrome, also known as Call-Fleming syndrome, was initially described in 1988, and is characterized by a clinical syndrome of headaches episodes, generally the “thunderclap” pattern, due to a deregulation of the vascular tonus, leading to segmentary cerebral vasoconstriction and secondary neurological deficits, including those by ischemic or hemorrhagic stroke. In this paper, we present two illustrative cases of this syndrome due to the use of sibutramine. To our knowledge, this situation hasn’t been described as related drug before.