Open AccessMultiple Mieloma Metastases In Brain Parenchyma
Author(s) -
Allison de Freitas Francisco,
Raul Fernando Pizzatto,
Gustavo Henrique Smaniotto,
Rodrigo Leite de Morais,
A. Morais,
Ricardo Nascimento Brito
Publication year - 2018
Publication title -
jornal brasileiro de neurocirurgia
Language(s) - English
Resource type - Journals
eISSN - 2446-6786
pISSN - 0103-5118
DOI - 10.22290/jbnc.v22i3.1021
Subject(s) - medicine , multiple myeloma , adjuvant radiotherapy , brain biopsy , parenchyma , central nervous system , radiation therapy , biopsy , infiltration (hvac) , pathology , stereotactic biopsy , immunohistochemistry , radiation oncology , radiology , physics , thermodynamics
Multiple myeloma in the central nervous system (CNS) is an extremely rare condition, described in over 100 cases in the literature. In this article, the authors report the case of a 55-year-old female patient, subjected to an autologous bonemarrow transplant, and, furthermore, to a brain tissue biopsy with immunohistochemistry confirmation, revealing infiltration by a great amount of plasma cells, compatible with the clinical history of multiple myeloma. The patient was then subjected to CNS adjuvant radiotherapy, with constant observation by clinical oncology and monthly pamidronate disodium prescription. Despite being an incurable pathology, radiation therapy showed important local control.