Open AccessREVIEW ON FAST DISSOLVING TABLET BY SOLID DISPERSION APPROACH
Author(s) -
P.Siva V.Namitha
Publication year - 2021
Publication title -
journal of medical pharmaceutical and allied sciences
Language(s) - English
Resource type - Journals
ISSN - 2320-7418
DOI - 10.22270/jmpas.v10i3.1071
Subject(s) - dissolution , dosage form , dispersion (optics) , solid state , materials science , patient compliance , polymer , dissolution testing , chromatography , nanotechnology , process engineering , biomedical engineering , computer science , chemistry , chemical engineering , medicine , composite material , engineering , physics , optics , emergency medicine , biopharmaceutics classification system
Tablet is found to be the most popular dosage form among all existing dosage form. However, in certain occurrences as a result of the huge size of dosage forms, and in the uncooperative, pediatric and dysphasia patients, it might make a few problems, to avoid this issues, another type of dosage form is created, which is known as fast dissolving tablet or mouth dissolving tablet. These are the high level dosage form which breaks down within seconds when placed on the toungue. Mouth dissolving tablets have become impressive consideration as a better option in contrast to others because of better convenience to patients. This review discusses the method of preparation, properties, mechanisms; capsules to be incorporated inside the mouth dissolving pill and evaluation of the drugs are emphasized. The solid dispersion is one of the established solubilization techniques for poorly water-soluble drugs. It is basically the interaction between drug and polymer, and hence it is found to be the determining factor in its design and performance. This review additionally summarizes our knowledge on solid dispersions both in the solid as well as liquid state.