Open AccessAnti-Inflammatory Activity of Mimosa hamata (Willd.)
Author(s) -
Naeem Khan,
B. C. Hatapakki
Publication year - 2019
Publication title -
journal of drug delivery and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2250-1177
DOI - 10.22270/jddt.v9i5-s.3596
Subject(s) - carrageenan , anti inflammatory , traditional medicine , granuloma , inflammation , edema , botany , biology , pharmacology , medicine , surgery , immunology
Anti-inflammatory activity of ethanolic extract of roots, stems and leaves Mimosa hamata was investigated at the doses of 200 and 400 mg/kg using carrageenan induced paw edema and cotton pellet granuloma technique in albino rats. The stem extracts showed significant activity in dose dependent manner as compared to control group. The observations suggested that the extract of M. hamata were effective in exudative and proliferative phases of inflammation i.e. in acute and chronic inflammation. The results obtained indicate that M. hamata has an anti-inflammatory activity that supports the folk medicinal use of the plant.
Keywords: Mimosa hamata, anti-inflammatory activity, carrageenan induced paw edema, cotton pellet granuloma.