Open AccessNanoparticulate drug delivery systems: A revolution in design and development of drugs
Author(s) -
Prashant Shukla,
Shweta Sharma,
P. V. S. N. Malleshwara Rao
Publication year - 2021
Publication title -
journal of drug delivery and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2250-1177
DOI - 10.22270/jddt.v11i5-s.5023
Subject(s) - drug delivery , nanotechnology , drug , nanoparticle , liposome , dendrimer , materials science , pharmacology , medicine , polymer chemistry
The recent developments in nanoparticle-based drug formulations have been helping to address issues around treating challenging diseases. Nanoparticles come in different sizes but usually vary between 100nm to 500nm. For the past few years there has been research going on in the area of drug delivery using particulate delivery systems. Various drug molecules have been modified for both pharmacokinetic and pharmacodynamic properties using nanoparticles as physical approach. Various polymers have been used in the formulation of nanoparticles for drug delivery research to increase therapeutic benefit, while minimizing side effects. Here, we review various aspects of nanoparticle formulation, characterization, effect of their characteristics and their applications in delivery of drug molecules and therapeutic genes.
Keywords: nanoparticles, applications in delivery, Liposomes, Dendrimers