Open AccessFormulation and Evaluation of Curcumin Gel Sanitizer
Author(s) -
Roja Maddi,
Surekha Perumalla,
Lalitha Kumari Sesham,
Seema Sultana Shaik,
Jithashma Tanniru,
Hima bindu Uppu,
Sri Lakshmi Kalasani,
Asiya Begum,
Rama Rao Nadendla
Publication year - 2021
Publication title -
journal of drug delivery and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2250-1177
DOI - 10.22270/jddt.v11i4-s.4985
Subject(s) - curcumin , hand sanitizer , phytochemical , curcuma , traditional medicine , chemistry , food science , antimicrobial , organoleptic , medicine , biochemistry , organic chemistry
Objective: the main intention of this research is to prepare a curcumin based herbal gel sanitizer by minimizing the alcoholic usage and to evaluate the anti-bacterial activity of this herbal sanitizer. Methods: curcumin gel sanitizer was prepared from the ethanolic extract of Curcuma longa along with addition of gel base prepared from the combination of carbapol-940 and HPMC-E15. Results: The curcumin gel sanitizer was formulated and evaluated for its phytochemical constituents present in curcumin, detection of active constituent of curcumin which was majorly responsible for the anti-microbial activity through HPTLC, organoleptic properties, irritancy test and the efficiency of anti-bacterial activity of curcumin was also evaluated and it is safe and effective against pathogens. Conclusion: As a natural herb, curcumin which was a household ingredient could also be effectively formulated as a sanitizer that reduces the side effects of alcoholic sanitizer products and is a best source that acts effectively against a numerous pathogens.
Keywords: curcumin, carbapol-940, Ethanolic extract, HPMC-E15 (hydroxypropyl methylcellulose), HPTLC, Pathogens,