Open AccessNanotechnology: A novel approach for treatment of skin disorder
Author(s) -
Tamanna,
Harmeet Singh
Publication year - 2021
Publication title -
journal of drug delivery and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2250-1177
DOI - 10.22270/jddt.v11i4-s.4945
Subject(s) - solid lipid nanoparticle , atopic dermatitis , acne , medicine , psoriasis , niosome , bioavailability , dermatology , imiquimod , liposome , nanocarriers , topical agents , dermis , skin barrier , drug delivery , pharmacology , drug , nanotechnology , chemistry , pathology , materials science , biochemistry , vesicle , membrane
Skin, the integument system; pertaining to our body which consists of mainly three layers (i) Epidermis (ii) Dermis (iii) Subcutaneous Tissue. It acts as a protective barrier against many diseases and infections. Skin disorders vary greatly in symptoms and severity. Some may be attributed to situational causes while others may be genetic like atopic dermatitis, melanoma, acne vulgaris, wound healing and psoriasis. Conventional therapies are used to analyze various topical disorders suffers from many limitations i.e. less efficacy, poor patient compliance, and poor bioavailability. Therefore, novel approaches should be investigated for the development of better treatment of the disease. Novel carriers such as Liposome, Niosomes, Ethosomes, Silver nanoparticles, Solid lipid nanoparticles are utilized through almost all the routes of administration to treat dermatological disorders. These Nano systems are used to provide targeted drug delivery and a site-specific delivery of dosage form at a particular receptor site and thus enhance the uptake of poorly soluble drugs and overcome the issues related to poor bioavailability. The root cause for the development of such carriers lies on making the existing drugs more effective and safe for the patients.
Keywords: Skin, Skin disorders, NDDS, Novel Carriers, Nanotechnology