Open AccessEvaluation of the effect of hydroalcoholic extracts of Cassia occidentalis seeds in neutrophil adhesion test in Rats
Author(s) -
Dhaval Patel,
Amish J. Patel,
Riddhi D Trivedi,
Viram J Parmar,
Urvisha V. Bangoriya
Publication year - 2021
Publication title -
journal of drug delivery and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2250-1177
DOI - 10.22270/jddt.v11i1-s.4569
Subject(s) - cassia , traditional medicine , adhesion , medicine , chemistry , pathology , alternative medicine , organic chemistry , traditional chinese medicine
Evaluation of the effect of hydroalcoholic extracts of Cassia occidentalis seeds in neutrophil adhesion test in Rats. The effect of oral administration of hydroalcoholic extract of Cassia occidentalis seeds on neutrophil has been studied and is compared with control group on rats. The differential leukocyte count (DLC) was performed by fixing the blood smears and staining with leucofine and percent neutrophils in each sample was determined. After the initial counts, blood samples were incubated with 80 mg/ml of nylon fibers for 10 min at 37ºC. Supplementation with hydroalcoholic extract of Cassia occidentalis seedss significantly decreased neutrophil adhesion. The results indicate that the seed of Cassia occidentalis is endowed with protected neutrophil adhesion.
Keywords: Cassia occidentalis, Neutrophil, analysis of variance