Open AccessLiposome Characterization, Applications and Regulatory landscape in US
Author(s) -
Alok Kumar,
Madhu Gupta,
Simran Braya
Publication year - 2021
Publication title -
international journal of drug regulatory affairs
Language(s) - English
Resource type - Journals
eISSN - 2321-7162
pISSN - 2321-6794
DOI - 10.22270/ijdra.v9i2.474
Subject(s) - liposome , drug , drug delivery , pharmacology , targeted drug delivery , pharmacokinetics , drug development , product (mathematics) , risk analysis (engineering) , biochemical engineering , chemistry , computational biology , nanotechnology , medicine , biology , materials science , engineering , mathematics , geometry
Liposomes are lipid based drug carrier whose therapeutic performance depends on their structure. Liposomes offer several advantages over the conventional drug like target drug delivery, reduced toxicity, and extended pharmacokinetics. Characterization and Identification of critical attribute of liposomal formulation and suitable strategies for control during product development is important for quality of the liposomal drug product. This paper discusses the current status of the liposomal drug product and strategy used in regulating liposome product. Despite of lack of regulatory guidelines many liposome formulations get approved which shows the potential of liposome drug products.