Open AccessKidney disease and hemodialysis: identification of blood biomarkers to detect heart failure and kidney failure
Author(s) -
Barbara Mayer,
Paula Costa,
Maria Elena Echevarría-Guanilo,
Silvana Silveira Kempfer,
Kleber Maciel da Silva Pieri
Publication year - 2020
Publication title -
revista colombiana de nefrología
Language(s) - English
Resource type - Journals
eISSN - 2500-5006
pISSN - 2389-7708
DOI - 10.22265/acnef.7.2.382
Subject(s) - medicine , heart failure , kidney disease , hemodialysis , life expectancy , kidney , intensive care medicine , population , environmental health
Objectives: to identify valid blood biomarkers to detect heart failure and kidney failure associated with kidney disease and hemodialysis.
Methods: systematic literature review conducted in August 2018 in the following: Web Of Science, PubMed, Scopus, Cinahal, Cochrane, Science Direct and Lilacs. The guiding question was: “What are the blood biomarkers used to detect heart failure and kidney failure?” A total of 537 publications were found, 94 of these appeared more than once, 383 were excluded after reading titles and abstracts, 32 were excluded after reading the full texts, and 10 were excluded in the quantitative and qualitative synthesis.
Results: 18 papers compose the final sample and report laboratory and imaging tests, instruments to assess the risk of kidney and heart failure, and also clinical management of the progression of kidney and heart failure. All the studies correlated risk of mortality and mortality.
Conclusion: laboratory tests are important to identifying kidney and heart failure and need to be used to improve clinical management of the hemodialysis treatment of people with chronic kidney disease in order to improve quality of life and life expectancy.