Open AccessNADPH oxidases in GtoPdb v.2021.3
Author(s) -
Albert van der Vliet
Publication year - 2021
Publication title -
iuphar/bps guide to pharmacology cite
Language(s) - English
Resource type - Journals
ISSN - 2633-1020
DOI - 10.2218/gtopdb/f993/2021.3
Subject(s) - nadph oxidase , superoxide , hydrogen peroxide , reactive oxygen species , enzyme , biochemistry , oxidase test , chemistry , thyroid , oxygen , biology , endocrinology , organic chemistry
The two DUOX enzymes were originally identified as participating in the production of hydrogen peroxide as a pre-requisite for thyroid hormone biosynthesis in the thyroid gland [9].NOX enzymes function to catalyse the reduction of molecular oxygen to superoxide and various other reactive oxygen species (ROS). They are subunits of the NADPH oxidase complex.