Open AccessTumour necrosis factor (TNF) receptor family in GtoPdb v.2021.3
Author(s) -
David J. MacEwan
Publication year - 2021
Publication title -
iuphar/bps guide to pharmacology cite
Language(s) - English
Resource type - Journals
ISSN - 2633-1020
DOI - 10.2218/gtopdb/f334/2021.3
Subject(s) - tumor necrosis factor alpha , medicine , inflammatory bowel disease , tumor necrosis factors , immunology , immunotherapy , arthritis , tumor necrosis factor receptor , tumor necrosis factor α , cancer , necrosis , inflammation , disease , cancer research , rheumatoid arthritis
Dysregulated TNFR signalling is associated with many inflammatory disorders, including some forms of arthritis and inflammatory bowel disease, and targeting TNF has been an effective therapeutic strategy in these diseases and for cancer immunotherapy [5, 6, 49].