Human Chronic Gonadotropin Concentrations in Very Early Pregnancy and Subsequent Preeclampsia | Zendy

Nader Z. Rabie | Zendy; Everett F. Magann | Zendy

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Human Chronic Gonadotropin Concentrations in Very Early Pregnancy and Subsequent Preeclampsia

Author(s) -

Nader Z. Rabie,

Everett F. Magann

Publication year - 2014

Publication title -

women s health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.363

H-Index - 39

eISSN - 1745-5065

pISSN - 1745-5057

DOI - 10.2217/whe.14.39

Subject(s) - preeclampsia , hum , odds ratio , pregnancy , medicine , human chorionic gonadotropin , obstetrics , in vitro fertilisation , gynecology , andrology , gestational age , endocrinology , biology , hormone , art , genetics , performance art , art history

Evaluation of: Asvold BO, Vatten LJ, Tanbo TG, Eskild A. Concentrations of human chorionic gonadotrophin in very early pregnancy and subsequent preeclampsia: a cohort study. Hum. Reprod. 29(6), 1153-1160 (2014). A total of 2405 consecutive singleton pregnancies were followed to determine if early HCG levels were associated with the development of preeclampsia. All pregnancies were conceived by in vitro fertilization, which allowed very accurate gestational age dating. HCG levels were obtained on day 12, and grouped into four categories ( 150). HCG levels less than 50 were associated with an odds ratio of 2.3 (95% CI: 1.2-4.7) for preeclampsia and and odds ratio of 4.2 (95% CI: 1.4-12.2) for severe preeclampsia. Early HCG levels may serve as a marker for the detection of preeclampsia.

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