Open AccessAdipose tissue-derived mesenchymal stem cells for breast tissue regeneration
Author(s) -
Mohammed A Banani,
Mohammed Rahmatullah,
Nawras Farhan,
Zoe Hancox,
Safiyya Yousaf,
Zohreh Arabpour,
Zoha Salehi Moghaddam,
Masoud Mozafari,
Farshid Sefat
Publication year - 2021
Publication title -
regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 63
eISSN - 1746-076X
pISSN - 1746-0751
DOI - 10.2217/rme-2020-0045
Subject(s) - adipose tissue , mesenchymal stem cell , regeneration (biology) , breast cancer , stem cell , tissue engineering , medicine , biology , pathology , bioinformatics , cancer , microbiology and biotechnology , biomedical engineering
With an escalating incidence of breast cancer cases all over the world and the deleterious psychological impact that mastectomy has on patients along with several limitations of the currently applied modalities, it's plausible to seek unconventional approaches to encounter such a burgeoning issue. Breast tissue engineering may allow that chance via providing more personalized solutions which are able to regenerate, mimicking natural tissues also facing the witnessed limitations. This review is dedicated to explore the utilization of adipose tissue-derived mesenchymal stem cells for breast tissue regeneration among postmastectomy cases focusing on biomaterials and cellular aspects in terms of harvesting, isolation, differentiation and new tissue formation as well as scaffolds types, properties, material–host interaction and an in vitro breast tissue modeling.