Open AccessFGF2: a key regulator augmenting tendon-to-bone healing and cartilage repair
Author(s) -
Jun Zhang,
Zi-Ming Liu,
Yuwan Li,
Qi You,
Jiahui Yang,
Ying Jin,
Gang Zou,
Jingfeng Tang,
Zhen Ge,
Yi Liu
Publication year - 2020
Publication title -
regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 63
eISSN - 1746-076X
pISSN - 1746-0751
DOI - 10.2217/rme-2019-0080
Subject(s) - tendon , cartilage , medicine , ligament , wound healing , surgery , bone healing , anatomy
Ligament/tendon and cartilage injuries are clinically common diseases that perplex most clinicians. Because of the lack of blood vessels and nerves, their self-repairing abilities are rather poor. Therefore, surgeries are necessary and also widely used to treat ligament/tendon or cartilage injuries. However, after surgery, there are still many problems that affect healing. In recent years, it has been found that exogenous FGF2 plays an important role in the repair of ligament/tendon and cartilage injuries and exerts a synergistic effect with endogenous FGF2. Therefore, FGF2 can be used as a new type of biomolecule to accelerate tendon-to-bone healing and cartilage repair after injury.