Open AccessPreliminary effects of low-intensity focused ultrasound treatment program for cancer-related neuropathic pain
Author(s) -
Ankur Patel,
Max Zhukosvky,
Shawn Sidharthan,
Rohan Jotwani,
Neal Rakesh,
Amitabh Gulati
Publication year - 2021
Publication title -
pain management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.402
H-Index - 21
eISSN - 1758-1877
pISSN - 1758-1869
DOI - 10.2217/pmt-2020-0099
Subject(s) - medicine , neuropathic pain , high intensity focused ultrasound , intensity (physics) , cancer pain , cancer , oncology , physical therapy , ultrasound , radiology , anesthesia , physics , quantum mechanics
Aim: To evaluate the effectiveness of low-intensity focused ultrasound (LIFU) therapy in the management of cancer-related neuropathic pain (CNP). Methods: A retrospective review with 22 patients with CNP treated with LIFU therapy (frequency 3 Hz, 3 W/cm 2 , pulse mode duty cycle 50%) was conducted. Results: Out of the 22 patients, 15 had CNP secondary to chemotherapy-induced peripheral neuropathy. Compared with baseline, there was a significant reduction in numeric pain rating scale (p < 0.001). Additionally, 76.5% of patients (n = 13) were considered to be responders to LIFU therapy. Conclusion: LIFU therapy may be a viable treatment modality in the management of CNP, specifically chemotherapy-induced peripheral neuropathy, with a minimal side effect profile. Larger, prospective studies with a structured protocol are necessary.