
Noninvasive vagal nerve stimulation for gastroenterology pain disorders
Author(s) -
Andrés Gottfried-Blackmore,
Aida Habtezion,
Linda Nguyen
Publication year - 2021
Publication title -
pain management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.402
H-Index - 21
eISSN - 1758-1877
pISSN - 1758-1869
DOI - 10.2217/pmt-2020-0067
Subject(s) - medicine , abdominal pain , chronic pain , stimulation , etiology , visceral pain , vagus nerve stimulation , anesthesia , intensive care medicine , vagus nerve , physical therapy , nociception , receptor
Abdominal pain continues to be a major challenge and unmet need in clinical practice. Normalization of bidirectional gut-brain signaling has generated much interest as a therapeutic approach to treat chronic abdominal pain. Vagal nerve stimulation (VNS) is emerging as a potential non-pharmacologic strategy for the treatment of abdominal pain. In this review paper, we will summarize the etiologies of chronic pain in gastrointestinal disorders and discuss the rational for VNS as a therapeutic approach to chronic abdominal pain, with particular emphasis in the gammaCore stimulator which allows for noninvasive VNS.