Open AccessRacial and ethnic minority patient participation in N-of-1 trials: perspectives of healthcare providers and patients
Author(s) -
Lyndonna Marrast,
Joseph Conigliaro,
Camille Chan,
Eun Ji Kim,
Joan Duer-Hefele,
Michael A. Diefenbach,
Karina W. Davidson
Publication year - 2021
Publication title -
personalized medicine
Language(s) - English
Resource type - Journals
eISSN - 1744-828X
pISSN - 1741-0541
DOI - 10.2217/pme-2020-0166
Subject(s) - ethnic group , viewpoints , clinical trial , focus group , medicine , health care , family medicine , gerontology , sociology , political science , art , law , visual arts , pathology , anthropology
Aim: Patients from racial and ethnic minority backgrounds in the USA have historically been under-represented in research trials. Understanding their viewpoints regarding participation in N-of-1 trials is imperative as we design and implement these studies. Materials & methods: We conducted six focus groups of racial and ethnic minority patients (n = 25) and providers (n = 9). We used content analysis to identify themes. Results: Our results noted the importance of considering family members in N-of-1 trial recruitment and participation, patients' desire for education as a design feature, for 'lifestyle' changes as a treatment option and for use of nonevidence-based treatments in the design of future N-of-1 trials. Conclusion: Personalized trials have the potential to change the way we deliver primary care and improve disparities for minorities.