Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians | Zendy

Kevin C. Brown | Zendy; Mina C. Hosseinipour | Zendy; Janelle M. Hoskins | Zendy; Ranjit K. Thirumaran | Zendy; Hsiao-Chuan Tien | Zendy; Ralf Weigel | Zendy; Jean Tauzie | Zendy; Ida Shumba | Zendy; Jatinder K. Lamba | Zendy; Erin G. Schuetz | Zendy; Howard L. McLeod | Zendy; Angela D. M. Kashuba | Zendy; Amanda Corbett | Zendy

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Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians

Author(s) -

Kevin C. Brown,

Mina C. Hosseinipour,

Janelle M. Hoskins,

Ranjit K. Thirumaran,

Hsiao-Chuan Tien,

Ralf Weigel,

Jean Tauzie,

Ida Shumba,

Jatinder K. Lamba,

Erin G. Schuetz,

Howard L. McLeod,

Angela D. M. Kashuba,

Amanda Corbett

Publication year - 2011

Publication title -

pharmacogenomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.541

H-Index - 91

eISSN - 1744-8042

pISSN - 1462-2416

DOI - 10.2217/pgs.11.132

Subject(s) - nevirapine , cyp2b6 , cyp3a4 , pharmacogenetics , constitutive androstane receptor , genotype , pharmacokinetics , pregnane x receptor , cyp2a6 , single nucleotide polymorphism , pharmacology , allele , cyp3a , cyp3a5 , biology , medicine , cytochrome p450 , genetics , gene , viral load , nuclear receptor , metabolism , virus , antiretroviral therapy , transcription factor

Genetic polymorphisms have the potential to influence drug metabolism and vary among ethnic groups. This study evaluated the correlation of genetic polymorphisms with nevirapine pharmacokinetics exposure in Malawians.

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