Open AccessUnraveling the effects of siRNA carrier systems on cell physiology: a multiparametric approach demonstrated on dextran nanogels
Author(s) -
Stefaan J. Soenen,
Lynn De Backer,
Bella B. Manshian,
Shareen H. Doak,
Koen Raemdonck,
Jo Demeester,
Kevin Braeckmans,
Stefaan C. De Smedt
Publication year - 2013
Publication title -
nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 109
eISSN - 1748-6963
pISSN - 1743-5889
DOI - 10.2217/nnm.12.208
Subject(s) - nanogel , nanocarriers , dextran , intracellular , chemistry , cell , nanotoxicology , microbiology and biotechnology , biophysics , oxidative stress , cell culture , toxicity , biology , biochemistry , drug delivery , genetics , organic chemistry
The extent of cell-nanoparticle interactions between a polycationic siRNA nanocarrier system (dextran nanogels) and cultured cells was analyzed.
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