Open AccessThe emergence of neoadjuvant therapy in advanced melanoma
Author(s) -
James Sun,
Д. А. Кириченко,
Jonathan S. Zager,
Zeynep Eroglu
Publication year - 2019
Publication title -
melanoma management
Language(s) - English
Resource type - Journals
eISSN - 2045-0893
pISSN - 2045-0885
DOI - 10.2217/mmt-2019-0007
Subject(s) - medicine , neoadjuvant therapy , melanoma , interim , immunotherapy , targeted therapy , clinical trial , intensive care medicine , oncology , cancer , cancer research , breast cancer , archaeology , history
The discovery of immunotherapy and targeted therapy has introduced new and effective treatment options for advanced melanoma, providing therapeutic options where none existed before. The natural extension of these novel therapies is to identify their role in the neoadjuvant setting. Neoadjuvant therapy for advanced melanoma is still in its infancy, with a wealth of clinical trials underway. Early results are promising, allowing for management of a disease that previously had few options. We review the current literature and interim results from several ongoing investigations to understand the current state of neoadjuvant treatment options and what is to come. These studies pave the way for further advancements in melanoma therapy.