Open AccessCancer and COVID-19: analysis of patient outcomes
Author(s) -
Mohamed Aboueshia,
Mohammad Hussein,
Abdallah S. Attia,
Aubrey Swinford,
Peter Miller,
Mahmoud Omar,
Eman A. Toraih,
Nakhle S. Saba,
Hana Safah,
Juan Duchesne,
Emad Kandil
Publication year - 2021
Publication title -
future oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.857
H-Index - 72
eISSN - 1744-8301
pISSN - 1479-6694
DOI - 10.2217/fon-2021-0121
Subject(s) - medicine , malignancy , covid-19 , retrospective cohort study , cancer , obesity , cohort , disease , cohort study , infectious disease (medical specialty)
Background: We sought to investigate the outcomes associated with COVID-19 disease in cancer patients. Methods: We conducted a retrospective cohort study of laboratory-confirmed COVID-19 patients. Results: Of the 206 patients included, 57 had at least one preexisting malignancy. Cancer patients were older than noncancer patients. Of the 185 discharged cases, cancer patients had a significantly higher frequency of unplanned reintubation (7.1% vs 0.9%, p < 0.049), and required longer hospital stay (8.58 ± 6.50 days versus 12.83 ± 11.44 days, p < 0.002). Regression analysis revealed that obesity and active smoking were associated with an increased risk of mortality. Conclusion: Outcomes in COVID-19 appear to be driven by obesity as well as active smoking, with no difference in mortality between cancer and noncancer patients.