Open AccessPredicting ambulatory recovery in acute ischemic stroke patients with thrombolytic therapy
Author(s) -
Matthew Scalise,
Leanne Brechtel,
Zachary Conn,
Benjamin Bailes,
Jordan Gainey,
Thomas I. Nathaniel
Publication year - 2020
Publication title -
future neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.419
H-Index - 32
eISSN - 1748-6971
pISSN - 1479-6708
DOI - 10.2217/fnl-2020-0002
Subject(s) - medicine , odds ratio , ambulatory , aphasia , paresis , logistic regression , thrombolysis , stroke (engine) , physical therapy , cardiology , surgery , myocardial infarction , mechanical engineering , psychiatry , engineering
Aim: The aim of this study was to determine the predictive value of clinical presentations on functional ambulation following thrombolytic therapy. Materials & methods: Logistic regression analysis was used to determine associations between functional ambulation and thrombolytic therapy. Results & conclusion: In the results, Hispanic ethnicity (odds ratio (OR): 2.808; p = 0.034; 95% CI: 1.08–7.30), high National Institute of Health Stroke Scale (NIHSS) (OR: 1.112; p ≤ 0.001; 95% CI: 1.06–1.17), weakness/paresis (OR: 1.796; p = 0.005; 95% CI: 1.19–2.71), Broca’s aphasia (OR: 1.571; p = 0.003; 95% CI = 1.16–2.12) and antihypertensive medication (OR: 1.530; p = 0.034; 95% CI: 1.03–2.26) were associated with an improved ambulation in patients without thrombolytic therapy. In thrombolytic treated patients, Broca’s aphasia was associated with improved functional outcome.