Open AccessDrug-based therapeutic strategies for COVID-19-infected patients and their challenges
Author(s) -
Khatereh Zarkesh,
Elaheh Entezar-Almahdi,
Parisa Ghasemiyeh,
Mohsen Akbarian,
Marzieh Bahmani,
Shahrzad Roudaki,
Rahil Fazlinejad,
Soliman Mohammadi-Samani,
Negar Firouzabadi,
Majid Hosseini,
Fatemeh Farjadian
Publication year - 2021
Publication title -
future microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.797
H-Index - 82
eISSN - 1746-0921
pISSN - 1746-0913
DOI - 10.2217/fmb-2021-0116
Subject(s) - herd immunity , covid-19 , pandemic , vaccination , transmission (telecommunications) , outbreak , medicine , epidemiology , population , intensive care medicine , immunization , environmental health , virology , immunology , disease , infectious disease (medical specialty) , immune system , pathology , electrical engineering , engineering
Emerging epidemic-prone diseases have introduced numerous health and economic challenges in recent years. Given current knowledge of COVID-19, herd immunity through vaccines alone is unlikely. In addition, vaccination of the global population is an ongoing challenge. Besides, the questions regarding the prevalence and the timing of immunization are still under investigation. Therefore, medical treatment remains essential in the management of COVID-19. Herein, recent advances from beginning observations of COVID-19 outbreak to an understanding of the essential factors contributing to the spread and transmission of COVID-19 and its treatment are reviewed. Furthermore, an in-depth discussion on the epidemiological aspects, clinical symptoms and most efficient medical treatment strategies to mitigate the mortality and spread rates of COVID-19 is presented.